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		<title>A Pediatric Board Forum by PBR Has MOVED!  &#187;  Topic: Absolute lymphocyte count in SCID etc.</title>
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		<pubDate>Fri, 10 Apr 2026 23:17:20 +0000</pubDate>
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					<guid>http://forum.pediatricsboardreview.com/forums/topic/absolute-lymphocyte-count-in-scid-etc/#post-460</guid>
					<title><![CDATA[Absolute lymphocyte count in SCID etc.]]></title>
					<link>http://forum.pediatricsboardreview.com/forums/topic/absolute-lymphocyte-count-in-scid-etc/#post-460</link>
					<pubDate>Thu, 22 Aug 2013 14:58:06 +0000</pubDate>
					<dc:creator>MikeBlyth</dc:creator>

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						<p>The notes say, for SCID, &#8220;Look for a low Absolute Lymphocyte Count (ALC) that is well below 40.&#8221; <em>Primary Immunodeficiency Diseases: Definition, Diagnosis, and Management</em> says &#8220;Absolute lymphocyte counts are often less than 1000, but normal lymphocyte counts do not exclude SCID,&#8221; and another article, &#8220;<a href="http://jcp.bmj.com/content/54/3/191.full" rel="nofollow">Diagnosis of severe combined immunodeficiency</a>,&#8221; says &#8220;an absolute lymphocyte count of less than 2.8 × 10e9/litre is 2 SD below the mean. When infants with infection have a count lower than this, it is highly likely that they have SCID.&#8221; Where does this very low criterion (ALC &lt; 40) come from?</p>
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