Vitamin D 1,25-OH is the ACTIVE form

kotl — Fri, 05 Oct 2012 01:17:34 +0000

For the second mnemonic under Vitamin D & Its Evaluation, I think it should read “Which one is the ACTIVE form?” instead of ‘inactive’ form. Since the subsequent lines talk about the 1,25-OH Vit D. Right?

Reply To: Vitamin D 1,25-OH is the ACTIVE form

ashish — Fri, 05 Oct 2012 01:18:17 +0000

You are correct and thank you for the catch!

Here’s the updated version:

VITAMIN D & ITS EVALUATION

The liver sends 25-Vitamin D to the kidneys where it gets hydroxylated to 1,25 Vitamin D (the active form). If looking for a nutritional deficiency, obtain a 25-Vitamin D level. SUPPLEMENT with 1,25 Vitamin D (the ACTIVE form). Typically, 25-Vit D is the first one you should check (especially if they ask for a screen).

MNEMONIC: Where is the Vitamin D produced that carries 2 numbers with it (1 and 25)? TWO organs = TWO kidneys = TWO numbers (1 and 25)!

MNEMONIC: Which one is the active form? Think of it this way… if you ingest a calcium containing food in its natural form, it will first go to the gut, then the liver, then the blood, then finally the kidneys! So keeping the above mnemonic in mind, it’s the Vitamin D with TWO numbers!

PEARLS: Here are some ways Vitamin D deficiency could present

* African-American (AA) breastfed child whose mom is not on Vitamin D supplementation

* African-American (AA) breastfed child whose mom is not getting enough sunlight

* Child with symptoms consistent with malabsorption

* Child with a history of epilepsy who is on anti-seizure medications

A Pediatric Board Forum by PBR Has MOVED! » Topic: Vitamin D 1,25-OH is the ACTIVE form

Vitamin D 1,25-OH is the ACTIVE form

Reply To: Vitamin D 1,25-OH is the ACTIVE form

VITAMIN D & ITS EVALUATION