Absolute lymphocyte count in SCID etc.

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    MikeBlyth
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    The notes say, for SCID, “Look for a low Absolute Lymphocyte Count (ALC) that is well below 40.” Primary Immunodeficiency Diseases: Definition, Diagnosis, and Management says “Absolute lymphocyte counts are often less than 1000, but normal lymphocyte counts do not exclude SCID,” and another article, “Diagnosis of severe combined immunodeficiency,” says “an absolute lymphocyte count of less than 2.8 × 10e9/litre is 2 SD below the mean. When infants with infection have a count lower than this, it is highly likely that they have SCID.” Where does this very low criterion (ALC < 40) come from?

    • This topic was modified 10 years, 8 months ago by  MikeBlyth.
    • This topic was modified 10 years, 8 months ago by  MikeBlyth.
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